Experience using 675 nm laser on three cases of Fitzpatrick skin type IV-V with melasma

Pamela et al., including Vitale, present a prospective case series evaluating the safety and efficacy of a 675 nm non-ablative laser for melasma in patients with Fitzpatrick skin types IV–V. Three Indonesian women underwent three monthly sessions, showing significant reductions in mMASI scores and visible improvement without adverse effects. The study highlights the laser's dual action on melanin and collagen with a favorable safety profile in darker phototypes, suggesting its potential as a safe, effective option for melasma in skin of color.

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Clinical evidence of high-power 675 nm laser system equipped with a faster treatment modality for the management of pigmented lesions and skin rejuvenation.

This article reports the first clinical case using topical exosomes derived from Lactobacillus plantarum to treat active acne. After 4 weeks of application, the patient showed marked reductions in papules, pustules, and inflammation, with no irritation or side effects—suggesting exosomes may be a promising non-antibiotic option for acne management.

Noninvasive Correction of Asymmetric Smiles Using Electrical Muscle Stimulation

This study shares clinical insights on hybrid filler protocols combining hyaluronic acid (HA) with hyperdiluted calcium hydroxylapatite (CaHA). The premixed formulation, injected with a cannula in fan or retrograde technique, provided improved skin quality, hydration, and firmness. The article includes tips for product ratios, areas of use, and adverse event prevention.

Management of Mixed Melasma on Darker Phototypes: A New and Safe Laser Therapy Treatment

This case series explores the use of a 675-nm diode laser for the treatment of mixed-type melasma in patients with Fitzpatrick phototypes III to V. Four women underwent one or two sessions using the RedTouchPro laser. The protocol resulted in notable improvements in both pigmentary and vascular components, with minimal discomfort and no significant side effects. Image-based assessment using the LifeViz system showed enhanced brightness, texture, and skin uniformity. The laser’s high affinity for melanin and collagen, along with integrated cooling, ensures a safe and effective approach to melasma in darker skin tones, even during summer months.

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